Preheat oven to 375 degrees and lightly grease a 9-inch pie plate. As an option, you may spread 1/2 tablespoon of butter over the plate then sprinkle with 2 tablespoons Parmesan to coat.
Scatter the crab, artichokes, spinach and cheese evenly in the pie plate.
In a large mixing bowl, whisk the remaining ingredients until well blended. Pour into pie plate. (You may need to gently work the egg mixture under the solid ingredients with a fork.)
Bake for 40 minutes or until just firm in the center. If the top begins to brown too much, cover lightly with a piece of foil. I typically cover for the last 10 minutes or so.
When cooked through, remove from oven and allow to rest for five minutes before serving.