Preheat the oven to 350 degrees F.
Place the salmon on a large, rimmed baking sheet. If you prefer to remove the skin, do not grease the sheet. If you’d like to keep the skin on, do grease the baking sheet. Tip: the salmon will be easier to transfer without breaking when the skin is left on.
Pour the white wine over the salmon. Next sprinkle with the brown sugar, rubbing to evenly distribute, followed by the salt and pepper. I don’t measure but give it an “average” sprinkle—not too light, not too heavy. (For those who like a precise measurement, I would say 1/2 teaspoon salt and 1/4 teaspoon pepper.)
Bake the salmon for approximately 18 to 20 minutes or until a quick-read thermometer registers 125 degrees F. A temperature reading of 120 degrees F. will be slightly undercooked in the thicker parts of the fillet–a reference temperature if you prefer the inside to still be slightly rare. Precise cooking time will vary based on the size and thickness of the fillet. Feel free to cut into the thickest portion of the fillet if not using a thermometer and/or adjust according to personal preference.
Remove the salmon from the oven and let cool. (You may absolutely enjoy this salmon warm, too.) Then cover with plastic wrap and refrigerate. When ready to serve, transfer the salmon to a serving platter. I find this easiest when using two of my biggest and longest spatulas. If you didn’t grease the baking sheet (so that you could remove the skin), simply run the spatula between the salmon’s flesh and skin. The skin will stick to the sheet. If the fillet breaks, don’t worry. Just piece it back together and garnish with lemon slices, cucumber slices, and/or fresh herbs. Serve with optional Creamy Dill sauce.